Astro Boy, created by Osamu Tezuka in 1963, is considered the first modern anime and helped to popularize the genre both in Japan and around the world.

Fullmetal Alchemist, created by Hiromu Arakawa in 2001, is a popular manga and anime series that explores themes of science, magic, and the consequences of human ambition.

Anime refers to animated works that are created in Japan and often feature colorful and stylized animation, complex storylines, and richly developed characters.