Fullmetal Alchemist, created by Hiromu Arakawa in 2001, is a popular manga and anime series that explores themes of science, magic, and the consequences of human ambition.

Japan's isolationist policy during the Edo period limited contact with the outside world but allowed for the development of unique cultural practices and traditions.

Ghost in the Shell, created by Masamune Shirow in 1989, is a popular anime and manga series that explores themes of cybernetics, artificial intelligence, and the nature of humanity.